All of the victims were believed to be part of a crew from utility company CenterPoint Energy that was trying to shut down a gas line, FOX 51 of Tyler, Texas, reported.
The extent of the injuries was not immediately known.
At least one house was damaged in the blast and fire, with an unknown number of nearby residents evacuated as the emergency response got underway, the station reported.
Responders set up a 500-foot perimeter around the blast and fire scene, FOX 26 of Houston reported.
Firefighters were able to get the blaze under control, the report said.
- [LLODO] Massive 8-alarm blaze breaks out in Queens apartment building
- [LLODO] Wildfire in Theodore Roosevelt National Park triples in size
- [LLODO] Los Angeles fire prompts rescue of people stranded on roof: report
- [LLODO] Oregon emergency crews, police responding to three-alarm fire at ethanol fuel facility
- [LLODO] Louisville church fire prompts arson investigation: report
- [LLODO] Phoenix police officer rescues family from burning home
- [LLODO] Massive fire engulfs home near DC’s Embassy Row; firefighter hurt
- [LLODO] New York dad-to-be killed in gender reveal explosion, police say