Barbara Higgins also had a brain tumor of her own while trying to get pregnant and had it removed.
Higgins and her husband, Kenny Banzhoff, of Concord, have been grieving for their late daughter Molly.
In recent years, the couple, who also have an older daughter, thought about having another child. They found an in vitro fertilization clinic in Boston that worked with them.
Higgins gave birth to a healthy boy named Jack on Saturday. He weighed 5 pounds, 13 ounces.
“Yes, I’m scared and I’m anxious, but I’m so excited,” Higgins told the Concord Monitor for a story published Friday.
Higgins, an avid runner who has been a high school track coach, said she did weight training until the day she went into labor.
In addition to Higgins’ struggles with her brain tumor, Banzhoff, 65, had been living with kidney disease and underwent a transplant.
According to Guinness World Records, the oldest woman to give birth was 66-year-old Maria del Carmen Bousada Lara, who had twins in Spain in 2006.